fludrocortisone will reduce the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
The anticonvulsant Qualities of diazepam and also other benzodiazepines can be partly or entirely resulting from binding to voltage-dependent sodium channels as an alternative to GABAA receptors.
Never take VALIUM if you: are allergic to diazepam or any with the ingredients in VALIUM. See the end of the Medication Guidebook for a complete listing of elements in VALIUM.
verapamil will raise the amount or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
cyclophosphamide will boost the degree or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified.
巴比妥类药物(比如:苯巴比妥) • 苯二氮平類藥物(比如:地西泮) • 氨己烯酸,及托吡酯
Keep away from or substitute An additional drug for these remedies when achievable. Examine for loss of therapeutic result if medication must be coadministered.
Lonafarnib may well raise the AUC and peak focus of CYP2C19 substrates. If coadministration unavoidable, keep an eye on for adverse reactions and reduce the CYP2C19 substrate dose in accordance with its accredited merchandise labeling.
iloperidone raises levels of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Iloperidone is really a time-dependent CYP3A inhibitor and could bring on amplified plasma levels of medication predominantly eliminated by CYP3A4.
Reduced Alertness or Coordination. Diazepam can impact your alertness or coordination. Will not generate or do other activities that demand alertness or coordination till you know the way diazepam affects you.
Avoid or substitute A further drug for these prescription drugs when achievable. Assess for lack of therapeutic influence if medication need to be coadministered. Modify dose In line with prescribing info if desired.
exercise as a neuronal voltage gated calcium channel blocker in rats.34 Furthermore, it binds to a singular benzodiazepine receptor,
Indicated for acute procedure of intermittent, stereotypic episodes of Recurrent seizure action (ie, seizure clusters, acute repetitive seizures) distinct from a patient’s regular seizure sample Utilised adjunctively in convulsive Problems, even though it hasn't proved practical as the sole therapy
debe more info saber que este medicamento le puede ocasionar somnolencia. No conduzca ningún vehículo ni opere maquinaria hasta que sepa cómo le afecta este medicamento.